Orally Administered Fish Medications Chemotherapeutics

Chemotherapeutic Dose Indication Remarks
Acetylsalicylic acid 5 mg/kg OID stress relief none
Ampicillin 10 mg/kg BID bacterial infection not advised. Ineffective
Ascorbic acid 700 mg/kg of food hypovitaminosis C none
Asprin 5 mg/kg OID stress relief none
Aureomycin 10 mg/kg bacterial infection none
Chloramphenicol palmitate 1 g/kg food OID

50-100 mg/kg fish

bacterial infection

bacterial infection

not advised. Ineffective
Chlortetracycline 10-20 mg/kg BID/OID bacterial infection many resistant bacteria
Cycloserine 3 mg/100 gm of food bacterial infection possibly effective against Mycobacteria
Dichlorvos 20 mg/kg ONCE nematodes none
Difloxacin 5 mg/kg OID bacterial infection low resistence potential
Dimetridazole 150 mg/100 g food OID, 5 days Hexamita spp. none
Erythromycin 20 mg/kg bacterial infection not advised. Ineffective
Erythromycin thiocyanate 100 mg/kg OID for 10 days

150 mg/kg OID for 14 days

bacterial infection

bacterial infection

not advised. Ineffective

not advised. Ineffective

Erythromycin phosphate 100 mg/kg OID for 10 days bacterial infection
not advised. Ineffective
Fendendazole 11 mg/kg OID twice nematodes none
Folic acid 5 mg/kg OID vitamin deficiency none
Furazolidone

.

25 mg/kg OID for 20 days antimicrosporidial inhibits spread of whirling disease, but does not cure.
Furoxone 25 mg/kg OID for 20 days antimicrosporidial inhibits spread of whirling desease,but does not cure
Gentamicin 0.75 mg/kg bacterial infection poorly absorbed in the gut. Some resistant strains.
Griseofulvin 50 mg/kg OID deep fungal infection none
Hydrocortisone 4 mg/kg BID anti-inflammatory none
Isoniazid 2 mg/kg OID Bradycardia, cardiac insufficiency none
Kanamycin 20 mg/kg OID

10 mg/kg QID

bacterial infection

bacterial infection

poorly absorbed in the gut. Some resistant strains
Kaopectate 1 ml/kg QID enteritis, gastritis none
Levamisole 10 mg/kg 3 doses 7 days apart nematodes none
Mebendazole 20 mg/kg weekly for three treatments nematodes none
Metronidazole 50 mg/kg OID for 5 days

1 g/100 g of food OID for 5 days

flagellate infection

Hexamita spp.

none

none

Minocycline 0.5 mg/kg OID bacterial infection, mycobacteriosis none
Naladixic acid

20 mg/kg OID bacterial infection none
Neomycin 20 mg/kg QID bacterial enteritis poorly absorbed in the gut. Some resistant strains
Nitrofurazone





50 mg/kg OID

75-100 mg/kg OID 5 to 15 days



20 mg/kg TID

bacterial enteritis

microsporidial infection



Aeromonas sp., Edwardsiella sp, Yersinia sp.

none

controls but does not eliminate Plesitophora sp. in golden shiners. Stops fish reproduction.

<1% bioavailable.

generally more effective than Chlorotetracycline. Resistant strains common.

Apparently not immunosupressive at these doses.

Penicillin G (NA) 125 mg/kg OID for 21 days bacterial kidney disease none
Penicillin (K) 40,000 units/kg QID bacterial infection none
Pepto-Bismol 2 ml/kg OID gastritis, enteritis none
Piperazine 110 mg/kg ONCE nematodes none
Praziquantel HCL

400 mg/100 g food OID for 7 days

500 mg/kg ONCE

trematodes, Diplostomum sanguinicola

cestodes

none

none

Quinacrine 75 mg BID for 3 days protozoan infection repeat in 3 days
Riboflavin 10 mg/kg OID deficiency none
Streptomycin 25 mg/kg OID broad spectrum antibacterial poorly absorbed from gut. Some resistant strains
Sulfadiazine 220 mg/kg Once, followed by 5 day at half initial dose s protozoal infection, bacterial infection none
Sulfamerazine 42 mg/kg OID prophylaxis for bacterial kidney disease in feed
Tribrissen 1 mg/kg OID for 14 days Broad spectrum antibiotic effective against Yersinia ruckeri, Escherichia, Streptococcus, Proteus, Salmonella, Pasteurella, and Shigella
Vitamin A 500 U/kg OID for 14 days hypovitaminosis none
Vitamin B12 200 ug/day Q3D hypovitaminosis, appetite stimulant none
Vitamin D 30 U/kg Q7D hypovitaminosis none
Vitamin E 100 IU/kg Q3D hypovitaminosis none